Lyophilization

Lyophilization

Some products are simply too sensitive and require lyophilization to maintain appropriate shelf-life and efficacy for their intended patient. BSM has a clean-in-place, steam-in-place lyo. We also have experience with lyophilizing products within a syringe which can reduce costly waste from hold-up volumes. All filling operations and transfer to the lyo are performed in permanently connected isolators.

Lyophilization

Lyophilization Details:

  • Container Sizes: Client Directed
  • Capacity: Client Directed – up to 10,000 2 mL vials
  • Operations: Manual or Semi-Automated – all Isolator Based
  • Components: Client Specified
  • Fully isolated filling environments
  • Lyo development and optimization services
Pump / Containment SystemScaleVial Size
Peristaltic or Piston/IsolatorClinical up to 10,0002 mL to 100 mL