From Bench to Bedside: The Journey of Oligonucleotide Drug Development and Sterile Filling

From Bench to Bedside: The Journey of Oligonucleotide Drug Development and Sterile Filling

About this white paper:

This white paper serves as a comprehensive guide to enhancing the formulation, lyo cycle development, and fill finish process of oligonucleotide therapeutics. The paper will describe the latest strategies and best practices for improving the quality and efficacy of oligo drug products. From identifying key factors in formulation development to optimizing the lyophilization process and ensuring sterile fill finish, this whitepaper provides valuable insights for researchers, scientists, and pharmaceutical professionals looking to stay ahead in this rapidly evolving field.

This white paper discusses how oligonucleotide drug product formulations are developed and optimized, the process of developing and optimizing a lyophilization cycle, how drug product sensitivities are managed through formulation, filtration, and filling, and simple and effective solutions to reduce drug product loss.